出版:
2022年2月22日
Making progress on Ambition Zero Carbon through collaboration with key partners and suppliers
澳门葡京赌博游戏的 partnership with Honeywell to develop next-generation respiratory inhalers with near-zero Global Warming Potential (GWP) propellant demonstrates our commitment to improving patient outcomes and protecting patient choice, 同时减少澳门葡京赌博游戏的环境足迹.
自从澳门葡京赌博游戏推出旗舰可持续发展计划“零碳雄心”以来， 2019冠状病毒病造成的破坏给世界各地带来了巨大变化. 保持不变的东西, 然而, is the climate emergency which has the potential to be one of the greatest threats to human health.1 与澳门葡京赌博游戏价值链上的合作伙伴一起, we're taking concrete steps to decarbonise the environmental impact of care in support of healthy people, 健康的社会和健康的地球.
Listen to our Senior Executive Team members discuss our delivery on Ambition Zero Carbon in this short video:
Advancing our next-generation pressurised metered-dose inhalers (pMDIs) with a near-zero Global Warming Potential (GWP) propellant
澳门葡京赌博游戏正在与霍尼韦尔合作开发下一代pMDI, 使用HFO-1234ze推进剂，其具有高达99.比目前用于呼吸系统药物的推进剂的全球升温潜能值低9%.2 考虑到pmdi的临床需求，这是一项极其重要的创新.3-7
在全球范围内，有多达3.39亿儿童和成人患有哮喘8 多达3.84亿人患有慢性阻塞性肺疾病(COPD).9 对其中许多人来说，pmdi是一种重要的治疗选择，3-7 因为这些吸入药物可以减少COPD恶化和哮喘发作, 哪些是潜在的危及生命的事件.10-11 然而, pMDIs contain small quantities of a type of greenhouse gas (GHG) to propel the medicine into the lungs.12
It is important to recognise that poor respiratory disease control can contribute significantly to a higher carbon footprint of respiratory care.13 因此, prioritising optimal disease management would not only improve patient outcomes but could also have a positive impact on the environment. 例如, data showed uncontrolled asthma is associated with an increased carbon footprint compared to well controlled asthma.13 The excess GHG emissions come from routine GP visits and hospital care resulting from asthma attacks plus an over-reliance on short-acting beta2-agonist inhalers (three or more inhalers/year).13
慢性呼吸系统疾病会严重影响患者的生命, 针对个别病人的需要量身定制治疗是至关重要的. We know that millions of patients globally use pMDIs to help prevent asthma attacks and COPD exacerbations. It is great to see near-zero global warming potential propellants in development that will ensure continued patient choice, as well as offer viable solutions to reducing the environmental impact of pressurised metered dose inhalers.
在实现“零碳雄心”承诺的轨道上
澳门葡京赌博游戏的 collaboration with Honeywell is one example of the progress we’re making on our sustainability commitments. 以科学为指导原则, we are delivering on our ambition to be zero carbon across our global operations by the end of 2025 and carbon negative across our entire value chain by 2030. At AstraZeneca all of our imported electricity now comes from renewable sources and by the end of 2021, we had achieved a 59% reduction in our Scope 1 and 2 GHG emissions against a 2015 baseline, 包括整合澳门葡京网赌游戏罕见病业务.13 澳门葡京赌博游戏的 2021年可持续发展报告 更详细地概述澳门葡京赌博游戏的进展和承诺.
把净零带到下一步
We recognise that working in collaboration with others is critical to drive system-wide change. 像许多其他公司一样, the majority of our emissions sits outside our own operations and therefore engagement across our entire value chain is critical for us to reduce our Scope 3 emissions. 这就是为什么澳门葡京赌博游戏设定了到2025年底的目标, 95% of our key suppliers and partners will have science-based targets to limit global warming to <1.5C.13
澳门葡京赌博游戏不能单独做到这一点. We’re committed to working closely with our supply chain to help others on their decarbonisation journey - and accelerate a system-wide shift to net zero. Sustainable procurement is critical to the future of business – but also to how the world operates
作为一个创始成员 激励 在COP26上启动的项目, we will continue our work to support the pharmaceutical supply chain to access renewable energy. 除了, our Chief Executive Officer Pascal Soriot is championing the Sustainable Markets Initiative (SMI) Health Systems Taskforce, 它由13位全球卫生领导人组成，旨在加速实现净零, 以患者为中心的医疗.
作为一个全球性的企业，推动科学的边界，提供改变生活的药物, we’re committed to working in partnership with our stakeholders to build a sustainable future.
引用:
1. 谁. 气候变化与健康. (在线). 可在:http://www.谁.int /新闻/说明书/细节/气候变化与健康问题. [最后访问日期:2022年2月].
2. 澳门葡京网赌游戏制药. 存档日期. HFO-1234ze的全球变暖潜势. (ID: ref - 140251)
3. Lavorini F. 向哮喘患者输送治疗性气雾剂的挑战. ISRN过敏. 2013;102418.
4. Usmani操作系统, 等. 吸入器选择指南. 选择适当的吸入器装置治疗成人哮喘或慢性阻塞性肺病. 2017. 可在:http://www.的指导方针.co.英国/呼吸/ inhaler-choice-guideline / 252870.文章[最后访问日期:2022年2月]
5. 罗氏N, 等. 加压计量吸入器从早期到现代装置的演变. J气雾剂给药. 2016;4:311–27.
6. Laube提单, 等. 关于新的吸入疗法，肺科专家应该知道什么. Eur呼吸器. 2011;37:1308-31.
7. Lavorini F, 等. Optimising inhaled pharmacotherapy for elderly patients with chronic obstructive pulmonary disease: the importance of delivery devices. 药物老化. 2016;33:461–73.
8. 全球哮喘网络. 《2018年全球哮喘报告. (在线). 可在:http://www.globalasthmareport.org/Global%20Asthma%20Report%202018.pdf. [最后访问日期:2022年2月].
9. Adeloye D, 等. 全球卫生流行病学参考小组(GHERG). 全球和地区COPD患病率估计:系统回顾和荟萃分析. J Glob Health. 2015; 5 (2): 020415.
10. Beasley RW，等. 布地奈德-福莫特罗治疗轻度哮喘的对照试验. [英]医学. 2019;380 (21):2020–2030.
11. Ferguson GT，等. Effect of budesonide/formoterol pressurized metered-dose inhaler on exacerbations versus formoterol in chronic obstructive pulmonary disease: the 6-month, randomized RISE (Revealing the Impact of Symbicort in reducing Exacerbations in COPD) study. 和地中海. 2017; 132: 31‐41
12. ·迈尔德尔铅、 等. 计量吸入器技术的进展:配方开发. aap PharmSciTech. 2014;15(2):434–455.
13. 澳门葡京网赌游戏制药. AstraZeneca progresses Ambition Zero Carbon programme with Honeywell partnership to develop next-generation respiratory inhalers. (在线). 可在:http://xv6.jieyangw.com/content/astraz/media-centre/press-releases/2022/澳门葡京网赌游戏-progresses-ambition-zero-carbon-programme-with-honeywell-partnership-to-develop-next-generation-respiratory-inhalers.html. [最后访问日期:2022年2月].